TIADERM

“A new generation of hyaluronic acid-based injectables featuring a molecular architecture inspired by the natural gradients of the ocean”. Nature does not rely on a single structure. In the marine world, structural diversity is not random, but a precise response to the surrounding physical environment. The ocean is not uniform; each depth presents: • different pressure • different density • different mechanical forces TIADERM® follows the same biological principle, using specific viscoelastic matrices designed for each anatomical depth. TEMPERATURE · INTEGRATION · ADHESION — TIA™ Technology An engineered molecular architecture designed for precise injections, optimal tissue integration, and predictable clinical results. T Temperature Our patented slow, low-temperature cross-linking process ensures: • Extended homogenization without compromising the HA polymer structure • Controlled, gradual cross-linking • Minimal BDDE content • HA particles precisely sized from 1 to 20 microns The outcome is a stable, homogeneous, and predictable 3D matrix, with each particle intentionally engineered for optimal performance. I Integration Cross-linked high-molecular-weight hyaluronic acid, combined with medium- and low-molecular-weight free HA, is integrated within the matrix, ensuring: • Dynamic hydration • Progressive biological modulation • Sustained biological activity The resulting 3D matrix remains active and adaptive, enabling the gradual, controlled release of free HA over time. A ADHESION Clinically relevant features: • Seamless tissue integration • Controlled plasticity • Modulated elasticity • Soft, natural feel • No migration By combining different molecular weights, particle morphology, and 3D organization, TIADERM® creates viscoelastic matrices specifically tailored to each clinical application. “The ocean teaches us that depth determines structure. TIA™ Technology demonstrates that molecular architecture drives predictable clinical behavior”